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上海宇劲生物孙经理 
·产品描述
Methylamp通用DNA甲基化试剂盒提供了一整套必需的试剂和方法，制备甲基化阳性对照用于甲基化研究.试剂盒包括已经酶促甲基化的人类基因组DNA和所有DNA修饰试剂.甲基化的人类DNA在MS-PCR中做阳性对照之前需要预先进行修饰.试剂盒的DNA修饰可以满足对10ug的人类基因组DNA的修饰（20次修饰反应）.本试剂盒是针对Methylamp DNA修饰试剂盒系列的分析实验进行设计的，也可以和其他DNA修饰或甲基化试剂盒联用.Methylamp通用DNA甲基化试剂盒提供了一整套必需的试剂和方法，制备甲基化阳性对照用于甲基化研究.试剂盒包括已经酶促甲基化的人类基因组DNA和所有DNA修饰试剂.试剂盒的DNA修饰可以满足对10ug的人类基因组DNA的修饰（20次修饰反应）.该通用DNA甲基化试剂盒内主要产品组份包括：Methylated humangenomic DNA U1 （DNA modifier powder） U2 （DNA modification solution） U3 （balance solution） U4 （DNA binding buffer） U5 （elution buffer） F-spin column F-collection tube 用户指南手册
·产品特点
1、生成甲基化阳性对照进行甲基化研究；
2、包括酶促甲基化的人类基因组DNA和所有修饰元件；
3、可以和Methylamp DNA修饰试剂盒系列或者其它DNA修饰试剂盒联用。
The Methylamp™ Universal Methylated DNA Kit provides a methylation-positive control for methylation studies. The kit includes the enzymatically methylated human genomic DNA and all components for DNA modification. Methylated human DNA needs to be modified before it is used as a positive control in MS-PCR. DNA modification reagents included in the kit are sufficient for modifying 10 µg of methylated human genomic DNA (20 modifications). This product is intended for use with the Methylamp™ DNA Modification Kit series. It can also be used with other DNA modification or methylation kits.
Product Citations
Xu Y et. al. (August 2020). TET2 expedites coronary heart disease by promoting microRNA-126 expression and inhibiting the E2F3/PI3K/AKT axis. Biochem Cell Biol.
LIANG Jian-qing et. al. (August 2018). Study on DNA methylation of substantia nigra and striatum in the rat model of Parkinson's disease induced by 6-OHDA Med J Chin PLA. 43(8)
Santarelli L et. al. (September 2015). Combined circulating epigenetic markers to improve mesothelin performance in the diagnosis of malignant mesothelioma Lung Cancer.
Kobune M et. al. (September 2012). Stromal cells expressing hedgehog-interacting protein regulate the proliferation of myeloid neoplasms. Blood Cancer J. 2:e87.
Suzuki R et. al. (December 2007). Infrequent hypermethylation of WIF-1 promoter in BCR/ABL-negative myeloproliferative disorders. Tokai J Exp Clin Med. 32(4):131-5.
Suzuki R et. al. (September 2007). Preferential hypermethylation of the Dickkopf-1 promoter in core-binding factor leukaemia. Br J Haematol. 138(5):624-31.
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