说明书：

DFOR.pdf

Application

• Direct determination of formaldehyde concentrations in biological, food and environmental samples

Key Features

• Safe. Non-radioactive assay.
• Sensitive and accurate. As low as 1.5 μM (45 ppb) formaldehyde can be quantified.
• Homogeneous and convenient. "Mix-incubate-measure" type assay. No wash and reagent transfer steps are involved.
• Robust and amenable to HTS: Can be readily automated on HTS liquid handling systems for processing thousands of samples per day.

Method

•  FL370/470nm

Samples

•  Biological, food, beverage,environment

Species

•  All

Size

•  100 tests

Detection Limit

•  1.5 μM (45 ppb)

Shelf Life

•  18 months

More Details

•  FORMALDEHYDE (methanal) is the simplest aldehyde. It is widely employed in industry for wide range of applications. Formaldehyde is also used as a disinfectant and is a commonly utilized tissue fixative and embalming agent. Formaldehyde is naturally present in all tissues and body fluids. Recently it has been shown that some cancer types exhibit elevated formaldehyde levels. Increased formaldehyde concentration in urine has been associated with prostate and bladder cancer. Thus, measuring formaldehyde in urine can be a very useful tool when studying cancer. BioAssay Systems newly designed Formaldehyde Assay Kit provides a convenient fluorimetric means to measure formaldehyde in biological samples. In the assay, formaldehyde is derivatized with acetoacetanilide in the presence of ammonia. The resulting fluorescent product is then quantified fluorimetrically (&lambdaexc/em = 370/470nm). The assay is simple, sensitive, stable and high-throughput adaptable. The assay can detect as low as 1.5 μM formaldehyde in biological samples.

·相关文献

Zhai, R et al (2016). Evidence for Conversion of Methanol to Formaldehyde in Nonhuman Primate Brain. Analylatical Cell Pathology (Amsterdam): 4598454. Assay: Formaldehyde in monkey CSF.

Yang, M et al (2014). Alzheimer's disease and methanol toxicity (part 2): lessons from four rhesus macaques (Macaca mulatta) chronically fed methanol. J Alzheimers Dis. 41(4): 1131-1147. Assay: Formaldehyde in monkey whole blood.